Acne vulgaris (AV) is an inflammatory disease that caused by excessive activity in sebaceous glands and aggravated by Propionibacterium acnes infection. Synthetic antibiotics such as clindamycin are often used in the treatment of acne vulgaris. but its use can cause irritation. resistance. https://www.marcelovicente.com/product-category/4a-46d-chestnut-brown/