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Design principles for ligand-sensing, conformation-switching ribozymes.

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Nucleic acid sensor elements are proving increasingly useful in biotechnology and biomedical applications. A number of ligand-sensing. conformational-switching ribozymes (also known as allosteric ribozymes or aptazymes) have been generated by some combination of directed evolution or rational design. Such sensor elements typically fuse a molecular recognition domain (aptamer) with a c... https://www.roneverhart.com/Playtex-Women-s-18-Hour-Ultimate-Shoulder-Comfort-Wireless-Bra-Nude-46C/
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